Which of the following is required on a prescription for a controlled substance?

A prescription for a controlled substance must include the date of issue as a fundamental requirement. This is essential for several reasons: it helps determine the validity of the prescription over time, addresses the potential for misuse or abuse, and complies with legal regulations that stipulate how long a prescription for a controlled substance can be considered valid. In many jurisdictions, including Ohio, prescriptions for controlled substances have specific duration guidelines that dictate when a prescription must be filled or refilled based on this date.

The inclusion of the date of issue is critical in monitoring prescription use and preventing problems associated with prescription drug abuse. By having this specific date, pharmacists and other healthcare providers can track the appropriateness of dispensing the medication and ensure compliance with state and federal regulations. This helps in maintaining an accurate medication profile for the patient and managing their treatment effectively.

While options like the patient's signature, pharmacy's address, and payment method may be relevant in different contexts, they are not mandated elements of a prescription for controlled substances according to regulatory standards. Therefore, the date of issue stands out as an essential requirement for the legality and management of controlled substance prescriptions.