Which of the following statements about Schedule II drugs is correct?

The statement regarding Schedule II drugs that is correct is that they can be ordered on a DEA 222 form. This form is specifically designed for the purchasing and transferring of Schedule I and II controlled substances. The requirement to use a DEA 222 form ensures that there is proper tracking and accountability for these highly regulated medications, which have a high potential for abuse and addiction.

The other statements regarding Schedule II drugs are not correct. For instance, Schedule II drugs cannot be refilled; federal law prohibits the refilling of prescriptions for these substances as a measure to control their distribution and use. Additionally, while prescriptions for Schedule II drugs must be filled within a set period, there is no indefinite expiration date; they typically expire after six months from the date written. Lastly, a valid prescription for a Schedule II drug must always have the prescriber's signature. Filling a prescription without a doctor's signature would violate legal and regulatory requirements governing controlled substances.