Which of the following statements about prescription refills is true?

The statement that patients must confirm refills each time is true because, in many circumstances, it is considered a best practice for pharmacists to ensure that patients are aware of their medications and actively participating in their treatment regimen. This helps to confirm that the patient still requires the medication and provides an opportunity for the pharmacist to offer counseling or assess any changes in the patient's condition.

While there may be some exceptions based on the nature of the medication or specific pharmacy policies, requiring patient confirmation helps reduce the risk of medication errors and ensures appropriate adherence to therapy. It also encourages a collaborative relationship between the pharmacist and the patient, enhancing medication management overall.

In contrast, the other statements do not reflect key legislative or professional standards relevant to pharmacy practice, where aspects of patient engagement and counseling are important parts of refilling prescriptions.